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CAS: 2760609-74-1
Chemical Name: CG-0255; (2Z)-2-[(4R)-1-[(1S)-1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]-4-(propan-2-yloxycarbonyloxymethylsulfanyl)piperidin-3-ylidene]acetic acid
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel thiol prodrugs based on clopidogrel active metabolite H4, being rapidly converted to H4 through fast one-step hydrolysis catalyzed by carboxylesterases, thus potentially overcoming clopidogrel resistance and many other issues caused by the reliance of clopidogrel on cytochrome P-450 (CYP)-mediated oxidative bioactivation
References:
https://www.sciencedirect.com/science/article/abs/pii/S022352342500738X
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