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CAS: 1628870-27-8
Chemical Name: TP-0184; 2-N-[3-Methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-N-(2-pyridin-2-ylpyridin-3-yl)pyrimidine-2,4-diamine
Purity: >98% (HPLC)
Novel ACVR1 inhibitor, inhibiting FLT3/ACVR1 to overcome FLT3 inhibitor resistance and hinder AML growth synergistically with venetoclax (GLXC-06797)
Reference:
https://www.nature.com/articles/s41375-023-02086-6
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