Glixx Laboratories Inc

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PM534

 

CAS: N/A

 

Chemical Name: (4R)-N-[(1R)-1-[4-(Cyclopropylmethoxy)-6-oxopyran-2-yl]butyl]-2-[(Z)-N-hydroxy-C-methylcarbonimidoyl]-4-methyl-5H-1,3-thiazole-4-carboxamide

 

 
GLXC-28189For Lab R&D Uses Only
        Cat No: GLXC-28189

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent tubulin inhibitor, targeting the entire colchicine binding domain of tubulin, covering four of the five centers of the pharmacophore model, showing high antitumor activity that efficiently overrides two resistance mechanisms in cells (detoxification pumps and tubulin βIII isotype overexpression)

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01775


Analytical data click for PDF file

 

 

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