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CAS: N/A
Chemical Name: (R)-N,N-Diethyl-2-((6-fluoro-2-oxo-4-(o-tolyl)-2H-chromen-7-yl)oxy)propanamide
Purity: >98% (HPLC)
Nove potent inhibitor of the human mitochondrial RNA polymerase (POLRMT), inhibiting tumor growth in MIA PaCa-2 xenograft tumor model with a tumor growth inhibition (TGI) rate of 64.52% demonstrating significant improvement compared to the positive control (44.80%)
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01178
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