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CAS: N/A
Chemical Name: CalB; (2S,3S)-2-[[(2S,3S)-2-[[(2S)-1-[(3S,9S,12S,15S,18S,20R,24S,26E,30S,33S)-15-[(2S)-butan-2-yl]-12,24-bis[(2R)-butan-2-yl]-20-hydroxy-9,30-bis(2-methylpropyl)-2,8,11,14,17,23,29,32-octaoxo-1,7,10,13,16,22,25,28,31-nonazatetracyclo[31.3.0.03,7.018,22]hexatriacont-26-ene-27-carbonyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoic acid
Purity: >98% (HPLC)
Natural anti-tubercular cyclic peptide, targeting the non-essential membrane protein Rv2113, inhibiting axenic and intracellular growth of Mycobacterium tuberculosis
References:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00221-6
https://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00266
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