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µOR inverse ago-NAM 368

 

CAS: N/A

 

Chemical Name: A1APU; 10105-368-30-605; Cmpd 368; 2-(2-((1-(5-(Benzyloxy)pyridin-3-yl)naphthalen-2-yl)thio)acetamido)-3-(3-methoxy-4-methylphenyl)-N-methylpropanamide

 

 
GLXC-29029For Lab R&D Uses Only
        Cat No: GLXC-29029

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel inverse agonist negative allosteric modulator (NAM) for the the µ-opioid receptor (µOR), significantly inhibiting met-enkephalin induced µOR activation of Gi, resulting in inhibition of µOR-induced signaling when bound to a variety of orthosteric agonists

 

References:

https://www.biorxiv.org/content/10.1101/2023.09.08.556921v1.full

https://www.nature.com/articles/nature22354

 

Analytical data click for PDF file

 

 

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