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RyR2 stabilizer/SERCA2a stimulator 12a




Chemical Name: 1,1'-(((4-(7-Methoxy-2,3-dihydrobenzo[f][1,4]thiazepin-4(5H)-yl)butyl)azanediyl)bis(butane-4,1-diyl))bis(cyclopropan-1-ol)


GLXC-27982For Lab R&D Uses Only
        Cat No: GLXC-27982


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Dual functional RyR2-stabilizing and SERCA2a-stimulating agent, preventing Ca2+ leak through ryanodine receptor 2 (RyR2) and enhancing cardiac sarco-endoplasmic reticulum (SR) Ca2+ load by activation of Ca2+-dependent ATPase 2a (SERCA2a), increasing ATP hydrolysis mediated by SERCA2a activity in cardiac microsomes, improving cardiac function in heart failure




Analytical data click for PDF file



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