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CAS: 2213926-11-3 (Dione form: 338418-81-8)
Chemical Name: 5-(4-Chlorophenyl)-3-hydroxy-1,5-dihydro-6H-pyrazolo[4,3-c]pyridazin-6-one; 5-(4-Chlorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]pyridazine-3,6(5H)-dione
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel inhibitor of SUMOylation E2 Ubc9, binding to Ubc9 with KD values of 1.93±0.62μM, significantly inhibiting RanGAP1 SUMOylation
Reference:
https://www.nature.com/articles/s41401-020-0405-7
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