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Glixx Laboratorie
CAS: 2995344-53-9
Chemical Name: CS_3a; JNC; 5-Chloro-3-(3-chlorobenzyl)-N-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine
Purity: >98% (HPLC)
Novel Potent and Selective YTHDC1 inhibitor (Kd = 49 nM), being selective against the cytoplasmic m6A-RNA readers YTHDF1-3 and YTHDC2 and showing antiproliferative activity against the acute myeloid leukemia (AML) cell lines THP-1, MOLM-13, and NOMO-1
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00599
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