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YTHDC1 inhibitor 40

 

CAS: 2995344-53-9

 

Chemical Name: CS_3a; JNC; 5-Chloro-3-(3-chlorobenzyl)-N-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine

 

 
GLXC-28597For Lab R&D Uses Only
        Cat No: GLXC-28597

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel Potent and Selective YTHDC1 inhibitor (Kd = 49 nM), being selective against the cytoplasmic m6A-RNA readers YTHDF1-3 and YTHDC2 and showing antiproliferative activity against the acute myeloid leukemia (AML) cell lines THP-1, MOLM-13, and NOMO-1

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00599

 

Analytical data click for PDF file

 

 

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