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CAS: 2413382-30-4
Chemical Name: tert-Butyl 2-[(9R)-7-[4-(3-aminoprop-1-ynyl)phenyl]-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
Purity: >98% (HPLC)
Novel specific degrader of BDR2 and BRD4, recruiting CRL4DCAF16 to induce degradation of BRD2/4, showing no degrading activities for BRD3 and other bromodomain containing proteins
Reference:
https://www.biorxiv.org/content/10.1101/2023.02.14.528511v1.full.pdf
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