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CAS: N/A
Chemical Name: 2-Chloro-3-((S)-1-((3-chloro-6-methoxy-5-(((((S)-5-oxopyrrolidin-2-yl)methyl)amino)methyl)pyridin-2-yl)oxy)-2,3-dihydro-1H-inden-4-yl)-N-(5-(((((S)-5-oxopyrrolidin-2-yl)methyl)amino)methyl)pyridin-2-yl)benzamide
Purity: >98% (HPLC)
Novel PD-L1 inhibitor through the blockade of PD-1/PD-L1 interaction and functional inhibition of the PD-L1 signal pathway, displaying high in vivo antitumor efficacy in the CT26 mouse model and activating the immune microenvironment and inducing PD-L1 degradation in the tumor
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01534
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