Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 23811-08-7
Chemical Name: (-)-Hinesol; 2-[(3R,5S,6S)-6,10-Dimethylspiro[4.5]dec-9-en-3-yl]propan-2-ol
Purity: >97% (HPLC)
Natural antitumor agent, effectively inhibiting the A549 and NCI-H1299 cells in a dose- and time-dependent manner, inducing cell cycle arrest at G0/G1 phase and apoptosis, decreasing phosphorylation of mitogen-activated protein kinase, extracellular signal-regulated kinase, IκBα, and p65 inhibited the expressions of Bcl-2, cyclin D1 and upregulated the expression of Bax
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Hinesol&sort=date
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