Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 121064-78-6
Chemical Name: (1R,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-1,11-dihydroxy-10-(((E)-3-(4-hydroxyphenyl)acryloyl)oxy)-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
Purity: >98% (HPLC)
Natural cancer stem cell (CSC) inhibitor, inhibiting breast cancer cell proliferation and mammosphere formation in a dose-dependent manner and reducing the CD44high/CD24low subpopulation and aldehyde dehydrogenase (ALDH)-expressing cell population as well as the expression of the self-renewal-related genes CD44, SOX2, and OCT4
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164992/
https://pubmed.ncbi.nlm.nih.gov/?term=3-O-trans-p-Coumaroyltormentic+acid+&sort=date
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