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TLR7 agonist 27b

 

CAS: N/A

 

Chemical Name: N6-Butyl-7-(4-((diethylamino)methyl)-2-methoxybenzyl)-7H-purine-2,6-diamine

 

 
GLXC-28596For Lab R&D Uses Only
        Cat No: GLXC-28596

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent TLR7-selective agonist (EC50 of 17.53 nM), demonstrating high hTLR7 selectivity (224 folds against TLR8), stimulating the secretion of proinflammatory cytokines in mouse macrophages and enhancing intranasal vaccine efficacy against influenza A virus in vivo

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00489

 

Analytical data click for PDF file

 

 

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