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CAS: N/A
Chemical Name: N6-Butyl-7-(4-((diethylamino)methyl)-2-methoxybenzyl)-7H-purine-2,6-diamine
Purity: >98% (HPLC)
Novel potent TLR7-selective agonist (EC50 of 17.53 nM), demonstrating high hTLR7 selectivity (224 folds against TLR8), stimulating the secretion of proinflammatory cytokines in mouse macrophages and enhancing intranasal vaccine efficacy against influenza A virus in vivo
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00489
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