Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2929308-79-0
Chemical Name: (2R,3S)-C271; (2R,3S)-1-acryloyl-3-(4-bromophenyl)-N-(quinolin-8-yl)azetidine-2-carboxamide
Purity: >98% (HPLC)
Novel specific, covalent inhibitor of RNA methyltransferase NSUN2, stereoselectively disrupting NSUN2-tRNA interactions in cancer cells, leading to a global reduction in tRNA m5C content
Reference:
https://onlinelibrary.wiley.com/doi/10.1002/anie.202311924
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