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Glixx Laboratorie
CAS: N/A
Chemical Name: (S)-5-((R)-3-((3S,3aR,5S,6R,7S,7aS)-5,6-Dihydroxy-3,7,7a-trimethyl-6-(3-methylbut-2-enoyl)-4-oxooctahydro-1H-inden-5-yl)butyl)-4-methylfuran-2(5H)-one
Purity: >98% (HPLC)
Natural immunosuppressive agent, inhibiting the activations of AKT-mTOR, JNK, p38 MAPK or ERK pathway in T cells and macrophages, significantly lowering the levels of IL-6 and TNF-α in peripheral blood serum, and ameliorating the multiorgan damages of LPS-induced sepsis mice at 25 mg/kg dose
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01759
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