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5-HT2CR agonist 8

 

CAS: 1216074-15-5

 

Chemical Name: 7-Chlorospiro[chromene-2,4'-piperidine]

 

 
GLXC-28155For Lab R&D Uses Only
        Cat No: GLXC-28155

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel, potent, selective, and Gq-biased 5-HT2C receptor partial agonist (Emax = 71.09%) with an EC50 value of 121.5 nM and no observed activity toward 5-HT2AR or 5-HT2BR, exhibiting no recruitment activity for β-arrestin and showing low inhibition of hERG at 10 μM

 

Reference:

https://pubs.acs.org/doi/10.1021/acsmedchemlett.3c00454


Analytical data click for PDF file

 

 

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