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Glixx Laboratorie
CAS: 480-23-9
Chemical Name: Isoluteolin; 3',4',5,7-Tetrahydroxyisoflavone; 3-(3,4-Dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Purity: >98% (HPLC)
Genistein metabolite, showing immune-controlling effects and myorelaxant activity, inhibiting the P. acnes-induced increases in IL-6 and IL-1α levels in human keratinocytes (HaCaTs), decreasing the IL-1α and IL-6 mRNA levels and inhibiting the phosphorylation of inhibitor of kappa-B kinase, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, and mitogen-activated protein kinase induced by P. acnes, also decreasing the expression of Ki67.
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Orobol&sort=date
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