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CAS: N/A
Chemical Name: tert-Butyl (S)-3-((2S,4R)-4-(fluorosulfonyl)-1-((R)-3-methyl-2-(3-methylisoxazol-5-yl)butanoyl)pyrrolidine-2-carboxamido)-3-(4-(4-methylthiazol-5-yl)phenyl)propanoate
Purity: >98% (HPLC)
Novel Von Hippel-Lindau (VHL) protein-targeted sulfonyl fluoride, covalently binding Ser110 in the HIF1α binding site
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02123
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