Glixx Laboratories Inc

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RMC-9805

 

CAS: 2922732-54-3

 

Chemical Name: RM-036; (2S)-2-Cyclopentyl-2-((S)-7-((2R,3R)-3-cyclopropyl-1-methylaziridine-2-carbonyl)-2,7-diazaspiro[4.4]nonan-2-yl)-N-((22S,63S,4S)-12-(5-(4-cyclopropylpiperazin-1-yl)-2-((S)-1-methoxyethyl)pyridin-3-yl)-10,10-dimethyl-5,7-dioxo-11-(2,2,2-trifluoroethyl)-61,62,63,64,65,66-hexahydro-11H-8-oxa-2(4,2)-morpholina-1(5,3)-indola-6(1,3)-pyridazinacycloundecaphane-4-yl)acetamide

 

 
GLXC-28442For Lab R&D Uses Only
        Cat No: GLXC-28442

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class, mutant-selective and orally bioavailable covalent tri-complex KRAS G12D(ON) inhibitor, inducing apoptosis and driving tumor regression in preclinical models of KRASG12D cancers

 

Reference:

https://aacrjournals.org/cancerres/article/83/7_Supplement/526/721097/Abstract-526-RMC-9805-a-first-in-class-mutant

 

Analytical data click for PDF file

 

 

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