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ASP6918

 

CAS: 2242418-18-2

 

Chemical Name: (S)-1-(7-(8-Ethoxy-7-(5-methyl-1H-indazol-4-yl)-2-((1-methylpiperidin-4-yl)oxy)-6-vinylquinazolin-4-yl)-2,7-diazaspiro[3.5]nonan-2-yl)prop-2-en-1-one

 

 
GLXC-29096For Lab R&D Uses Only
        Cat No: GLXC-29096

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent, covalent KRAS G12C inhibitor with IC50 of 28 nM in cell-free assays, and pERK inhibition IC50 of 3.7 nM in NCI-H1373 cells

 

Reference:

https://www.sciencedirect.com/science/article/abs/pii/S0968089623004297

 

Analytical data click for PDF file

 

 

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