Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2242418-18-2
Chemical Name: (S)-1-(7-(8-Ethoxy-7-(5-methyl-1H-indazol-4-yl)-2-((1-methylpiperidin-4-yl)oxy)-6-vinylquinazolin-4-yl)-2,7-diazaspiro[3.5]nonan-2-yl)prop-2-en-1-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel highly potent, covalent KRAS G12C inhibitor with IC50 of 28 nM in cell-free assays, and pERK inhibition IC50 of 3.7 nM in NCI-H1373 cells
Reference:
https://www.sciencedirect.com/science/article/abs/pii/S0968089623004297
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