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CAS: N/A
Chemical Name: 2-(4-(2-((S)-1-(3,4-Difluorophenyl)-6-oxopiperidin-2-yl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)-N-(2-(4-(((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)methyl)phenyl)pyrimidin-5-yl)acetamide
Purity: >98% (HPLC)
Novel highly potent and efficient CBP/p300 degrader, potently inhibiting the growth of AML cells with low nanomolar IC50 value and effectively degrading CBP and p300 proteins in a concentration- and time-dependent manner
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02195
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