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CARM1 Degrader 3b




Chemical Name: (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(4-((1-((1-(2-(4-(3-(methyl((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)carbamoyl)phenoxy)phenoxy)acetyl)piperidin-4-yl)methyl)piperidin-4-yl)methyl)piperazin-1-yl)acetamido)butanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide


GLXC-27741For Lab R&D Uses Only
        Cat No: GLXC-27741


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Novel potent and selective coactivator-associated cellular arginine methyltransferase 1 (CARM1) degrader (DC50 = 8 nM and Dmax > 95%), resulting in potent downregulation of CARM1 substrate methylation and inhibition of cancer cell migration in cell-based assays




Analytical data click for PDF file



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