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CAS: 3021581-79-0
Chemical Name: PROTAC 42i; 3-Amino-6-(4-(N-(6-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)amino)-6-oxohexyl)sulfamoyl)phenyl)-N-phenylpyrazine-2-carboxamide
Purity: >98% (HPLC)
Novel ataxia telangiectasia and RAD3-related (ATR) kinase PROTAC, selectively decreasing ATR and phospho-ATR without affecting related kinases ATM and DNA-PKcs.
Reference:
https://www.sciencedirect.com/science/article/pii/S0223523424000473
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