Glixx Laboratories Inc

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Glixx Laboratorie

 

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BBO-8520

 

CAS: 2893809-51-1

 

Chemical Name: 4-((R)-4-((2S,5R)-4-Acryloyl-2,5-dimethylpiperazin-1-yl)-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-6-(trifluoromethyl)quinazolin-7-yl)-2-amino-7-fluorobenzo[b]thiophene-3-carbonitrile

 

 
GLXC-28446For Lab R&D Uses Only
        Cat No: GLXC-28446

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class, direct inhibitor of KRASG12C (ON), locking GTP-bound KRASG12C in the state 1 conformation resulting in rapid and blocking effector binding

 

References:

https://link.springer.com/article/10.1007/s40265-023-01980-8

https://aacrjournals.org/cancerres/article/84/7_Supplement/ND07/742758

 

Analytical data click for PDF file

 

 

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