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PARP1/c-Met Inhibitor 16


CAS: 2944101-99-7


Chemical Name: 4-(4-Fluoro-3-(4-(4-(2-(6-oxo-3-(pyridin-3-yl)pyridazin-1(6H)-yl)ethoxy)quinolin-7-yl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one


GLXC-28379For Lab R&D Uses Only
        Cat No: GLXC-28379


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Novel highly potent dual inhibitor, exhibiting excellent inhibitory activities against PARP1 (IC50 = 3.3 nM) and c-Met (IC50 = 32.2 nM), demonstrating good antiproliferative effects on HR-proficient cancer cell lines and those resistant to PARP1 inhibitors




Analytical data click for PDF file



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