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Glixx Laboratorie
CAS: 1853254-97-3
Chemical Name: Nendratareotide Uzatansine; (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-(((R)-2-((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-(4-hydroxybenzyl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamido)-3-amino-3-oxopropyl)disulfaneyl)propanoyl)-N-methyl-L-alaninate
Purity: >98% (HPLC)
Novel somatostatin receptor 2 (SSTR2)-targeting maytansinoid conjugate, targeting high levels of DM1 to SSTR2-expressing xenograft tumors
References:
https://pubmed.ncbi.nlm.nih.gov/?term=PEN-221&sort=date
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