Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1889284-33-6
Chemical Name: 2-((3'R,4S)-3'-Fluoro-5'-(1-(2-(methylamino)-2-oxoethyl)-1H-pyrazol-4-yl)-2,5-dioxo-2',3'-dihydrospiro[imidazolidine-4,1'-inden]-1-yl)-N-(4-fluorobenzyl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide
Purity: >98% (HPLC)
Novel potent P300/CBP inhibitor, inhibiting p300-mediated H3K9 acetylation (IC50 = 33 nM), DUX4-mediated transcription, and proliferation of CIC-DUX4 sarcoma (CDS) cells, suppressing tumor growth
References:
https://pubmed.ncbi.nlm.nih.gov/?term=iP300w&sort=date
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