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EGFRL858R/T790M/ACK1 inhibitor 21a

 

CAS: N/A

 

Chemical Name: N-(3-((6-Chloro-2-((1-ethyl-1H-pyrazol-4-yl)amino)quinazolin-4-yl)amino)phenyl)acrylamide

 

 
GLXC-28256For Lab R&D Uses Only
        Cat No: GLXC-28256

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent dual EGFRL858R/T790M/ACK1 inhibitor with IC50s at 23 nM and 263 nM, respectively, showing significant antitumor effects and good safety in ADZR xenograft-bearing mice

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01934

 

Analytical data click for PDF file

 

 

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