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YCH1899

 

CAS: 3032451-66-1

 

Chemical Name: 4-(3-(3-(5-Bromofuran-2-yl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one

 

 
GLXC-27698For Lab R&D Uses Only
        Cat No: GLXC-27698

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

New-generation antiresistant PARP inhibitor, exhibiting distinct antiproliferation activity against olaparib- and talazoparib-resistant cells, with IC50 values of 0.89 and 1.13 nM, respectively, retaining sensitivity in drug-resistant cells with BRCA1/2 restoration or 53BP1 loss

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00821


Analytical data click for PDF file

 

 

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