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AEP inhibitor 18

 

CAS: 2978521-26-3

 

Chemical Name: (2S,4R)-N-((S)-5-Amino-5-oxopent-1-yn-3-yl)-4-fluoro-1-(1-(4-(trifluoromethoxy)phenyl)cyclopropane-1-carbonyl)pyrrolidine-2-carboxamide

 

 
GLXC-28145For Lab R&D Uses Only
        Cat No: GLXC-28145

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

The first orthosteric, selective, orally bioavailable, irreversible, and brain penetrant inhibitor of asparagine endopeptidase (AEP), reducing Tau N368 fragment both in vitro and in vivo

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01804

Analytical data click for PDF file

 

 

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