Glixx Laboratories Inc

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Glixx Laboratorie

 

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Bruceine B

 

CAS: 25514-29-8

 

Chemical Name: NSC-132793; Methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-3-acetyloxy-10,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate

 

 
GLXC-19177For Lab R&D Uses Only
        Cat No: GLXC-19177

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Natural inhibitor of c-Maf, inhibiting multiple myeloma (MM) cell proliferation and inducing MM cell apoptosis in a caspase-3-dependent manner, displaying potent antimyeloma activity by inducing the degradation of the transcription factor c-Maf, downregulating Otub1, USP5, and the expression of CCND2 and ITGB7

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=Bruceine+B&sort=date

 

Analytical data click for PDF file

 

 

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