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CAS: 340808-65-3
Chemical Name: 4-({[4-(4-Chlorophenyl)-3-cyano-6-(thiophen-2-yl)pyridin-2-yl]sulfanyl}methyl)benzoic acid
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel human GCN5 inhibitor with the IC50 value of 3.1 ± 0.2 μM, occupying the binding pocket of acetyl-CoA cofactor, retarding cell proliferation and blocking the acetylation of H3K14 leading to cell apoptosis and cell cycle arrest at the G1 phase in MV4-11 cell lines
Reference:
https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra10074h
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