Glixx Laboratories Inc

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GLPG3312

 

CAS: 2340388-72-7

 

Chemical Name: N-Cyclopropyl-2-(difluoromethoxy)-6-methoxy-4-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)benzamide

 

 
GLXC-28071For Lab R&D Uses Only
        Cat No: GLXC-28071

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective pan-SIK inhibitor (IC50: 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3), demonstrated both anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01428

 

Analytical data click for PDF file

 

 

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