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CAS: N/A
Chemical Name: 3-((1-Methyl-2-oxo-1,2-dihydro-6H-benzo[6,7]azepino[4,3,2-cd]isoindol-6-yl)methyl)-N-(1-methylpiperidin-4-yl)benzamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and selective BRD4 BD2 inhibitor (IC50: 1.6 nM and 328-fold selectivity over BRD4 BD1), possessing potent effects on regulating the differentiation of Th17 cells and reducing the levels of Th17-related cytokines by affecting the activation of STAT3 and NF-κB
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01028
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