Glixx Laboratories Inc

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Bo-Mt-Ge

 

CAS: N/A

 

Chemical Name: (6-(((1S,4aS,7aS)-4-(Methoxycarbonyl)-1-((((5-methyl-2-((methyl(2-(methyl(((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)carbonyl)amino)ethyl)carbamoyl)oxy)-3-(((3-oxo-3H-phenoxazin-7-yl)oxy)methyl)benzyl)oxy)carbonyl)oxy)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl)methoxy)-6-oxohexyl)triphenylphosphonium bromide

 

 
GLXC-26828For Lab R&D Uses Only
        Cat No: GLXC-26828

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel multimodal molecule channel blocker with high biosafety, specifically inhibiting the UCP2 activities, decreasing the H+ influx in the matrix, regulating the electrochemical gradient, and depleting the endogenous GSH, which synergistically constitute a unique MoA to active apoptotic CSC death, counteracting the therapeutic resistance via a two-pronged tactic: drug efflux pump P-glycoprotein downregulation and antiapoptotic factor (e.g., Bcl-2) inhibition

 

Reference:

https://pubs.acs.org/doi/10.1021/jacs.2c12587

 

Analytical data click for PDF file

 

 

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