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BAY-985

 

CAS: 2101925-20-4

 

Chemical Name: 1-(4-{(1R)-1-[2-({6-[6-(Dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one

 

 
GLXC-22085For Lab R&D Uses Only
        Cat No: GLXC-22085

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and highly selective TBK1/Ikkε inhibitor, inhibiting the cellular phosphorylation of interferon regulatory factor 3 (IRF3) and displaying antiproliferative efficacy in the melanoma cell line SK-MEL-2, but showing only weak to moderate antitumor activity in the SK-MEL-2 human melanoma xenograft model

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01460

 

 

Analytical data click for PDF file

 

 

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