Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1422180-49-1
Chemical Name: (4S,7S,9aS)-8,8-Dimethyl-4-((S)-2-(methylamino)propanamido)-5-oxo-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)octahydropyrrolo[2,1-b][1,3]oxazepine-7-carboxamide
Cat No: GLXC-11160
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Novel Smac mimetic, demonstrating potent cell-killing effects in several subtypes of breast, ovarian, and prostate cancer cell lines but only when the DR ligand TRAIL or another such apoptosis inducer is co-administered
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953502/
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414821/
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