Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 380351-29-1
Chemical Name: 1-[3,5-Bis(4-bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-chloro-ethanone
Purity: >98% (HPLC)
Recruiter of the E3 ubiquitin ligase RNF114, binding to cysteine 8 (C8) in the intrinsically disordered region of RNF114 (RNF114-C8; IC50 = 470 nM) and inhibitor, RNF114-induced, autoubiquitination and p21 ubiquitination in a cell-free assay
Reference:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(21)00005-2
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