Glixx Laboratories Inc

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UNC6934

 

CAS: 2561494-77-5

 

Chemical Name: N-Cyclopropyl-3-oxo-N-(4-(pyrimidin-4-ylcarbamoyl)benzyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide

 

 
GLXC-22088For Lab R&D Uses Only
        Cat No: GLXC-22088

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent antagonist of NSD2-PWWP1 with a Kd (SPR) of 80 ± 18 nM, being selective for NSD2-PWWP1 over 14 other PWWP domains including NSD3-PWWP1, the closest on the phylogenetic tree, disrupting the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells

 

Ref: https://www.nature.com/articles/s41589-021-00898-0

 

Analytical data click for PDF file

 

 

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