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CAS: 2415537-51-6
Chemical Name: N-(2-(2-(3-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)propanamido)ethoxy)ethyl)acrylamide
Purity: >98% (HPLC)
Novel potent selective ALKi with low toxicity to normal cells, covalently binding to Cys1259, a cysteine located outside the ALK active site
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01707
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