Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1246668-32-5
Chemical Name: 2-Hydroxy-N-((1S,2S,6S)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)quinoline-3-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines
References:
https://pubmed.ncbi.nlm.nih.gov/?term=PBS-1086&sort=date

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