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Glixx Laboratorie
CAS: 1073612-91-5
Chemical Name: CY09; (Z)-4-((4-Oxo-2-thioxo-3-(3-(trifluoromethyl)benzyl)thiazolidin-5-ylidene)methyl)benzoic acid
Cat No: GLXC-10947
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Novel selective NLRP3 inhibitor, directly binding to the ATP-binding motif of NLRP3 NACHT domain and inhibiting NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation
References:
https://link.springer.com/article/10.1007/s12264-020-00544-0
https://link.springer.com/article/10.1007%2Fs11695-020-04571-8
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