Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 5-Benzyl-3-fluoro-11,12-dihydrodibenzo[b,f][1,5]diazocin-6(5H)-one
Purity: >98% (HPLC)
First-generation allosteric EGFR inhibitor, binding to the allosteric site of EGFR along with ATP that leads to inhibition of cell proliferation and arrest of EGFR L858R/T790M/C797S signalling
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381467/
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862338/
3) https://link.springer.com/article/10.1007/s43440-020-00131-0
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