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CAS: N/A
Chemical Name: N-((3-(4-(4-(2-((R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]azepin-6-yl)acetamido)butoxy)-3-fluorophenyl)-4,5-dihydroisoxazol-5-yl)methyl)acrylamide
Purity: >98% (HPLC)
Novel selective BRD4 short isomer degrader through E2 recruitment, demonstrating degradation of only the short, but not long, isoform of BRD4 in both HEK293T and MDA-MB-231 cells
Reference:
https://pubs.acs.org/doi/10.1021/acschembio.3c00040
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