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BRD4 short isomer degrader NF90

 

CAS: N/A

 

Chemical Name: N-((3-(4-(4-(2-((R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]azepin-6-yl)acetamido)butoxy)-3-fluorophenyl)-4,5-dihydroisoxazol-5-yl)methyl)acrylamide

 

 
GLXC-27166For Lab R&D Uses Only
        Cat No: GLXC-27166

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel selective BRD4 short isomer degrader through E2 recruitment, demonstrating degradation of only the short, but not long, isoform of BRD4 in both HEK293T and MDA-MB-231 cells

 

Reference:

https://pubs.acs.org/doi/10.1021/acschembio.3c00040

 

Analytical data click for PDF file

 

 

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