Glixx Laboratories Inc
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Chemical Name: 2-(2-(2-(4-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide
Purity: >98% (HPLC)
Novel PROTAC-mediated degrader, binding fewer off-target kinases than ibrutinib does, inducing BTK knockdown, recruiting BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome
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