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Elzovantinib

 

CAS: 2271119-26-5

 

Chemical Name: TPX-0022; (6S)-12-Amino-2-ethyl-45-fluoro-6-methyl-9-oxo-5-oxa2,8-diaza-1(5,3)-pyrazolo[1,5-a]pyrimidina-4(1,2)-benzenacyclononaphane-46-carbonitrile

 

 
GLXC-26839For Lab R&D Uses Only
        Cat No: GLXC-26839

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent, oral-active inhibitor of SRC, MET and c-FMS (IC50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively)

 

Reference:

https://aacrjournals.org/cancerres/article/81/13_Supplement/1444/667382/Abstract-1444-TPX-0022-a-potent-MET-SRC-CSF1R

https://aacrjournals.org/cancerres/article/79/13_Supplement/1325/633441/Abstract-1325-TPX-0022-a-polypharmacology

 

Analytical data click for PDF file

 

 

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