Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: 7-(4-(2-(4-(tert-Butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-1-yl)-N-hydroxyheptanamide
Purity: >98% (HPLC)
Novel Inhibitor of p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs) with the IC50 values of 140, 910 and 17.5 nmol/L against MDM2, HDAC1, and HDAC6, respectively, showing the tumor growth inhibition (TGI) in the A549 xenograft model was 65.4%, higher than that of SAHA and Nutlin at the same dose (TGI=57.3% and 44.0%, respectively)
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