Glixx Laboratories Inc

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MTK458

 

CAS: 2499962-58-0

 

Chemical Name: (R)-N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-6-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

 

 
GLXC-27505For Lab R&D Uses Only
        Cat No: GLXC-27505

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent activator of PINK1, binding PINK1 directly, stabilizing it in an active conformation, and clearing mitochondrial aggregates via PINK1-dependent mitophagy in cells and decreased ubiquitin phosphorylation in the brain and plasma from PD animal models

 

Reference:

https://www.biorxiv.org/content/10.1101/2023.02.14.528378v2


Analytical data click for PDF file

 

 

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