Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 1-(4-(8-Amino-3-(1-methylcyclopropyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-fluorophenyl)urea
Purity: >98% (HPLC)
Novel VDR-coactivator inhibitor, inhibiting ovarian cancer cell proliferation, activating caspase-3, cleaving poly (ADP-ribose) polymerase 1 (PARP1), and phosphorylated mitogen-activated protein kinases (MAPK), JUN N-terminal kinase/stress-activated protein kinase (JNK/SAPK) and p38, also inhibiting the expression of a vitamin D receptor target gene.
Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633305/
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